Rp-Diastereoselective synthesis of dinucleoside methylphosphonates by the phosphoramidite approach

This publication has 27 references indexed in Scilit:

• Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells
  Nucleic Acids Research, 1998
• Mixed-Backbone Oligonucleotides Containing Phosphorothioate and Methylphosphonate Linkages as Second Generation Antisense Oligonucleotide
  Nucleosides and Nucleotides, 1997
• Probing Contacts to the DNA Backbone in the trp Repressor−Operator Sequence-Specific Protein−Nucleic Acid Complex Using Diastereomeric Methylphosphonate Analogues
  Biochemistry, 1997
• The chirality problem in P-substituted oligonucleotides
  Perspectives in Drug Discovery and Design, 1996
• Synthesis and Thermodynamics of Oligonucleotides Containing Chirally Pure RP Methylphosphonate Linkages
  Nucleic Acids Research, 1996
• Development of Antisense and Antigene Oligonucleotide Analogs
  Progress in Nucleic Acid Research and Molecular Biology, 1996
• Synthesis of specific diastereomers of a DNA methylphosphonate heptamer, d(CpCpApApApCpA), and stability of base pairing with the normal DNA octamer d(TpGpTpTpTpGpGpC)
  Nucleic Acids Research, 1994
• Oligonucleoside Methylphosphonates as Antisense Reagents
  Nature Biotechnology, 1991
• Antisense oligonucleotides: a new therapeutic principle
  Chemical Reviews, 1990
• Octa(thymidine methanephosphonates) of partially defined stereochemistry: synthesis and effect of chirality at phosphorus on binding to pentadecadeoxyriboadenylic acid
  Nucleic Acids Research, 1990