Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA
- 1 November 1979
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 282 (5738) , 471-477
- https://doi.org/10.1038/282471a0
Abstract
A synthetic fowl plague virus (FPV) haemagglutinin gene has been cloned in bacteria and the complete sequence of the RNA gene deduced. It is 1,742 nucleotides long and the mRNA codes for 563 amino acids in an uninterrupted sequence. The nature of some of the important domains in the haemagglutinin has been established, and their structure is discussed in relation to their function. Extensive amino acid sequence homologies exist between FPV and human influenza haemagglutinins.Keywords
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