Effects of exogenous ubiquinone-10 on endogenous ubiquinone-10 in canine plasma and on electron transport enzymes in leucocytes.

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Abstract
The distribution of exogenous ubiquinone-10 in canine plasma was examined using deuterium-labeled ubiquinone-10 in conjunction with a computerized gas chromatography-mass spectrometry system. Electron transport enzymes in canine leukocytes were also studied. An increase in the plasma level of exogenous ubiquinone-10 did not affect the level of endogenous ubiquinone-10, and it was reflected in increased activities of the electron transport enzymes (succinate dehydrogenase Co Q reductase, succinate cytochrome c reductase and succinate oxidase) in leukocytes.