Decrease in plasma volume from intraabdominal trauma in rats
- 1 May 1989
- journal article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 33 (4) , 272-276
- https://doi.org/10.1111/j.1399-6576.1989.tb02906.x
Abstract
Intraabdominal surgery tends to lower circulating blood volume by mechanisms unrelated to bleeding. This phenomenon was investigated in chloralose anesthetized rats. Plasma volume was determined with radiolabelled albumin. Animals were subjected to a standardized abdominal trauma, eliciting minimal bleeding and evaporation, and others served as controls. The trauma decreased plasma volume and increased hematocrit significantly, whereas the plasma concentration of labelled albumin followed a similar time course in traumatized animals and in controls. It is concluded that experimental abdominal trauma may decrease blood volume by a loss of fluid with virtually the same albumin concentration as that of plasma.Keywords
This publication has 11 references indexed in Scilit:
- Lymph Flow from the Peritoneal Cavity in CAPD PatientsPublished by Springer Nature ,1986
- INCREASED VASCULAR PERMEABILITY: A MAJOR CAUSE OF HYPOALBUMINAEMIA IN DISEASE AND INJURYThe Lancet, 1985
- Computer Models for Metabolic Studies on Plasma ProteinsAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1985
- Nature of the disturbance in the body fluid compartments during and after surgical operationsBritish Journal of Surgery, 1979
- Transcapillary Escape Rate of Albumin and Plasma Volume in Essential HypertensionCirculation Research, 1973
- Fluid volume and albumin kinetics occurring with major surgeryPublished by American Medical Association (AMA) ,1972
- Fluid Shifts during the Surgical PeriodAnnals of Surgery, 1966
- Blood Losses and Plasma Volume Shifts During and Following Major Surgical OperationsAnnals of Surgery, 1962
- Acute Change in Extracellular Fluids Associated with Major Surgical Procedures *Annals of Surgery, 1961