Preparation of Functionalized Oxazolines
- 1 September 1992
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 22 (17) , 2543-2554
- https://doi.org/10.1080/00397919208021650
Abstract
The preparation of several oxazolines substituted at C-2 by an hetero substituted methyl group is reported. 2-Aminomethyl, 2-azidomethyl, 2-nitromethyl and 2-hydroxymethyl oxazolines were obtained by substitution of the corresponding 2-halogenomethyl oxazolines. On the other hand, 2-benzyloxycarbonylaminomethyl, 2-thiophenylmethyl, 2-selenophenylmethyl oxazolines were prepared by condensation of the appropriate iminoether with a β-aminoalcohol.Keywords
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