Restriction map variation in the Adh region of Drosophila.

Publisher Website
Google Scholar
Abstract
Restriction maps of a 12,000-nucleotide region containing the alcohol dehydrogenase (Adh) locus of the 2nd chromosome of Drosophila were determined for 18 independent 2nd chromosome stocks of D. melanogaster established from several natural populations and 5 closely related Drosophila spp. [D. simulans, D. mauritiana, D. yakuba, D. teissieri and D. erecta]. All of the detected map differences appear to lie outside the Adh coding block. Four polymorphic restriction sites and 4 insertion/deletion variants were identified among D. melanogaster chromosomes. The estimated heterozygosity per nucleotide site was 0.006. The relative distributions of restriction sites and insertion/deletion variations among subpopulations and species suggest that the insertion/deletion variation may be mildly deleterious.