CuBr/rac-BINOL-Catalyzed N-Arylations of Aliphatic Amines at Room Temperature
- 7 December 2006
- journal article
- research article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 72 (2) , 672-674
- https://doi.org/10.1021/jo062060e
Abstract
We have developed an efficient and readily available catalyst system CuBr/racemic BINOL (1,1‘-binaphthyl-2,2‘-diol) that catalyzes N-arylation of aliphatic amines at room temperature, and this inexpensive catalyst system is of high selectivity and tolerance toward various functional groups in the substrates.Keywords
This publication has 12 references indexed in Scilit:
- Highly efficient and practical phosphoramidite–copper catalysts for amination of aryl iodides and heteroaryl bromides with alkylamines and N(H)-heterocyclesTetrahedron, 2006
- Mild and efficient copper-catalyzed N-arylation of alkylamines and N–H heterocycles using an oxime-phosphine oxide ligandTetrahedron, 2005
- Amino Acid Promoted CuI-Catalyzed C−N Bond Formation between Aryl Halides and Amines or N-Containing HeterocyclesThe Journal of Organic Chemistry, 2005
- A mild and practical copper catalyzed amination of halothiophenesTetrahedron, 2005
- Modern Synthetic Methods for Copper‐Mediated C(aryl)-O, C(aryl)-N, and C(aryl)-S Bond FormationAngewandte Chemie International Edition in English, 2003
- Copper-catalyzed amination of aromatic halides with 2-N,N-dimethylaminoethanol as solventTetrahedron Letters, 2003
- Mild Method for Ullmann Coupling Reaction of Amines and Aryl HalidesOrganic Letters, 2003
- Mild and Efficient Copper-Catalyzed Amination of Aryl Bromides with Primary AlkylaminesOrganic Letters, 2003
- Tetrahedron report number 163Tetrahedron, 1984
- Ueber eine neue Darstellungsweise von PhenyläthersalicylsäureEuropean Journal of Inorganic Chemistry, 1904