In Vitro Activities of OPT-80 and Comparator Drugs against Intestinal Bacteria
- 1 December 2004
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 48 (12) , 4898-4902
- https://doi.org/10.1128/aac.48.12.4898-4902.2004
Abstract
The activities of OPT-80 against 453 intestinal bacteria were compared with those of seven other drugs. OPT-80 showed good activity against most clostridia, staphylococci, and enterococci, but streptococci, aerobic and facultative gram-negative rods, anaerobic gram-negative rods, and Clostridium ramosum were resistant. Poor activity against anaerobic gram-negative rods may maintain colonization resistance.Keywords
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