Nitrone cycloadditions: synthesis of (±)-andrachamine
- 1 January 1990
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 8,p. 2323-2327
- https://doi.org/10.1039/p19900002323
Abstract
The usefulness of the cycloaddition of alkenes to 2-alkyl-2,3,4,5-tetrahydropyridine oxides for the preparation of trans-2,6-dialkylpiperidines is confirmed by a stereoselective synthesis of (±)-andrachamine. Peroxy acid oxidation of 9-oxa-1-azabicyclo[4.3.0]nonanes does not lead regioselectively to the corresponding 2-alkyl-2,3,4,5-tetrahydropyridine oxide, as had previously been claimed.This publication has 14 references indexed in Scilit:
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