Thallium-201 Distribution in the Thyroid: Relationship to Thyroidal Trapping Function

Publisher Website
Google Scholar
Abstract
Experiments were undertaken to determine the behavior of 201Tl in the thyroid in relation to the iodide-trapping mechanism in rats. Iodide trapping was compared to thyroidal 201Tl trapping 30 min after i.v. injection. 201Tl uptake followed iodine uptake in control rats, TSH[thyrotropin]- and T3[triiodothyronine]-treated rats but did not decrease in the same manner as iodide concentration in perchlorate-treated rats. These studies suggest that 201Tl distribution in the thyroid may reflect the cationic side of the iodide pump or possible thyroidal blood flow.