Respiration of Rat Liver Homogenates Following Prolonged Cold Exposure

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Abstract
One month exposure to 5 [plus or minus] 1[degree]C resulted in a general increase in the activity of enzyme systems responsible for the aerobic oxidations of liver tissue. The magnitude of the increase varied from substrate to substrate with a minimum value of 48.4% with no substrate and a maximum value of +37.2% with succinate. The data suggest that the increase in liver metabolism following cold exposure is traceable to an increase in the activity or amount of particulate enzymes. Differences in the pattern of in vitro O2 consumption following cold exposure were also noted.

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