Monoclonal antibodies against hepatitis A virus
- 1 November 1983
- journal article
- research article
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 18 (5) , 1237-1243
- https://doi.org/10.1128/jcm.18.5.1237-1243.1983
Abstract
Three monoclonal antibodies (K2-4F2, K3-2F2, and K3-4C8) of the immunoglobulin G2a class were raised against hepatitis A virus. The specificity of these antibodies was confirmed by immune electron microscopy, solid-phase radioimmunoassay, and in vitro neutralization in cell culture. Binding studies suggested that they all recognize closely related antigenic determinants. These monoclonal antibodies should prove to be of great value as diagnostic and research reagents.This publication has 26 references indexed in Scilit:
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