Isoenzymes and Myocardial Infarction
- 15 September 1960
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 263 (11) , 531-536
- https://doi.org/10.1056/nejm196009152631102
Abstract
PLASMA and serum enzyme-activity alterations have proved useful as laboratory parameters in the diagnosis of myocardial disease.1 Among the enzymes employed to reflect myocardial necrosis are aldolase, glutamic oxalacetic transaminase, lactic dehydrogenase and malic dehydrogenase. Although the quantitative and serial changes in blood enzymes observed in myocardial infarction are characteristic, they are not specific in that other states such as those of liver, biliary and pancreatic tract and skeletal muscle may result in similar changes. In addition, the administration of drugs such as chlorpromazine, promazine, bishydroxycoumarin, pyrazinamide and opiates may result in elevations of serum enzymes similar to those observed . . .Keywords
This publication has 4 references indexed in Scilit:
- MULTIPLE FORMS OF ENZYMES: TISSUE, ONTOGENETIC, AND SPECIES SPECIFIC PATTERNSProceedings of the National Academy of Sciences, 1959
- INCREASING CLINICAL SIGNIFICANCE OF ALTERATIONS IN ENZYMES OF BODY FLUIDSAnnals of Internal Medicine, 1959
- OBSERVATIONS ON THE HETEROGENEITY OF MALIC AND LACTIC DEHYDROGENASE IN HUMAN SERUM AND RED BLOOD CELLS1Journal of Clinical Investigation, 1958