Abstract
This presentation discusses the increasing clinical importance of the aspect of clinical enzymology dealing with the use of body fluid enzyme alterations in the diagnosis of disease. The material discussed is concerned with a selected group of the more recently introduced measurements of enzyme activities of the noncellular components of serum, plasma, cerebrospinal fluid and serous effusions as these body fluid enzyme alterations pertain to cardiology, gastro-enterology, neurology and oncology. No attempt is made to review completely the increasingly large experience and literature in this field of clinical enzymology.

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