Relationship Between Methodological Trial Quality and the Effects of Selective Digestive Decontamination on Pneumonia and Mortality in Critically Ill Patients
Open Access
- 18 July 2001
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 286 (3) , 335-340
- https://doi.org/10.1001/jama.286.3.335
Abstract
Nosocomial pneumonia is the most frequent infection among mechanically ventilated patients treated in intensive care units (ICUs) and has been associated with increased morbidity, antibiotic use, and prolonged length of stay. Prevention of nosocomial pneumonia, therefore, remains a challenge for intensive care medicine.1Keywords
This publication has 19 references indexed in Scilit:
- Selective digestive decontamination in patients in intensive careJournal of Antimicrobial Chemotherapy, 2000
- Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?Published by Elsevier ,1998
- Decrease in nosocomial pneumonia in ventilated patients by selective oropharyngeal decontamination (SOD)Intensive Care Medicine, 1997
- Randomized, controlled trial of selective digestive decontamination in 600 mechanically ventilated patients in a multidisciplinary intensive care unitCritical Care Medicine, 1997
- Predictive ability of meta-analyses of randomised controlled trialsThe Lancet, 1995
- Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trialsJAMA, 1995
- Effect of selective decontamination of the digestive tract on respiratory tract infections and mortality in the intensive care unitThe Lancet, 1991
- Reducing sepsis in severe combined acute renal and respiratory failure by selective decontamination of the digestive tractCritical Care Medicine, 1990
- Intestinal decontamination for control of nosocomial multiresistant gram-negative bacilli. Study of an outbreak in an intensive care unit: Brun-Buisson C, Legrand P, Rauss A, et al. Ann Intern Med 1989;110:873-81. Reprint requests: Christian Brun-Buisson, MD, Service de Reanimation Medicale, Hoˆpital Henri Mondor, 94010 Creteil, FranceAmerican Journal of Infection Control, 1990
- Prevention of Colonization and Subsequent Infection in Critically Ill Patients: a Prospective, Randomized StudyPublished by Springer Nature ,1989