Hypoparathyroidism during Pregnancy: Treatment with Calcitriol
- 1 April 1981
- journal article
- letter
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 52 (4) , 810-813
- https://doi.org/10.1210/jcem-52-4-810
Abstract
A pregnant woman suffering from idiopathic hypoparathyroidism was treated with calcitriol [0.5–2 µg/day 1,25 dihydroxyvitamin D3 (1,25-(OH)2D3)]. Her twin infants were delivered by cesarian section at 37 weeks of gestation. Laboratory investigations in the perinatal period disclosed: 1) normal serum calcium and phosphorus levels in the mother, 2) normal babies with no clinical or biochemical signs of hyperparathyroidism, 3) a low serum level of 25-hydroxyvitamin D despite a normal serum level of 1,25-(OH)2D in the mother, and 4) a low level of 25-hydroxyvitamin D and a high level of 1,25-(OH)2D in cord serum in both infants. It is suggested that calcitriol is an effective treatment of hypoparathyroidism during pregnancy and produces no ill effects on the baby.Keywords
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