Mean residence time for drugs subject to reversible metabolism
- 1 July 1987
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 39 (7) , 565-567
- https://doi.org/10.1111/j.2042-7158.1987.tb03181.x
Abstract
Conventional methods based on moment analysis lead to biased estimates of the mean residence time for drugs subject to reversible metabolism. A stochastic approach is described which enables unbiased estimation of the mean residence time.This publication has 7 references indexed in Scilit:
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