The circularity of mitochondrial DNA.
- 1 October 1966
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 56 (4) , 1215-1222
- https://doi.org/10.1073/pnas.56.4.1215
Abstract
Evidence has been presented that mitochondrial DNA of L cells exists in circular form either when extruded from osmotically lysed organelles or extracted by phenol. In contrast, nuclear DNA is linear. Mitochondrial DNA appears to be membrane-bound at one or more sites. The molecular weight of mitochondrial DNA was estimated by electron microscopic and by chemical methods. Two to 6 ring molecules of molecular weight 10 x 106 may be present in single mitochondrion. Some of the implications of these findings were discussed.This publication has 25 references indexed in Scilit:
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