NorC, a New Efflux Pump Regulated by MgrA of Staphylococcus aureus
Open Access
- 1 March 2006
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 50 (3) , 1104-1107
- https://doi.org/10.1128/aac.50.3.1104-1107.2006
Abstract
NorC, a new efflux pump, like NorB, contributes to quinolone resistance that includes resistance to moxifloxacin and sparfloxacin in Staphylococcus aureus. norC expression, like that of norB and tet38 , is negatively regulated by MgrA, and overexpression of both norC and norB contributes to the quinolone resistance phenotype of an mgrA mutant.Keywords
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