Haemostasis in kala-azar
- 1 January 1970
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 64 (4) , 581-587
- https://doi.org/10.1016/0035-9203(70)90080-5
Abstract
20 patients with kala-azar were studied to evaluate their haemostatic status. 16 showed significant abnormality. In 11 multiple haemostatic defects were present. Thrombocytopenia alone or in combination with other defects, was noted in 8. One-stage prothrombin time, and/or thromboplastin generation test showed patterns resembling deficiency of factors V, VII, VIII, IX, X, XI and platelet factor 3. Deficiency of factor V was confirmed in 2 and that of factor VIII in one. Deficiency of factor XIII was noted in 2. Repeat studies, after recovery from kala-azar, were done in 8. In 7 of these the tests had become normal and in the eighth, marked improvement was noticed.Keywords
This publication has 6 references indexed in Scilit:
- Transplantation of the SpleenAnnals of Internal Medicine, 1968
- The Prothrombin Consumption Time TestAmerican Journal of Clinical Pathology, 1966
- The Thromboplastin Generation TestJournal of Clinical Pathology, 1953
- THE NATURE OF THE BLEEDING IN JAUNDICEJAMA, 1938
- A METHOD FOR THE SIMULTANEOUS ENUMERATION OF BLOOD PLATELETS AND RETICULOCYTESArchives of internal medicine (1908), 1932
- A CLINICAL STUDY OF THE COAGULATION TIME OF BLOODThe Lancet Healthy Longevity, 1913