Gut Propulsion in Mice Infected with Trichinella spiralis

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Abstract
Previous investigators have shown that T. spiralis increases intestinal motility and propulsion. Primary infection with T. spiralis in the mouse increased gut propulsion, measured by the movement of nonabsorbable chromatography beads, on day 5 after infection but not 9 days after infection. Both cortisone acetate, an anti-inflammatory agent, and Lomotil, which reduces gut motility, could suppress the increase in gut propulsion seen 5 days after infection. Early inflammation may influence peristaltic activity and propulsion of intestinal contents.