Isolation of ceramide phosphorylethanolamine from the blowfly Calliphora erythrocephala

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Abstract
Methods for isolating ceramide phosphorylethanolamine from the blowfly are described, and the physical and chemical characteristics of this compound are given. In C. erythrocephala it is probable that in the absence of readily available choline the tissue synthesizes ceramide phosphorylethanolamine to replace sphingomyelin in membrane function. Both phospholipids would exist as zwitterions at a physiological pH, and it is known that in the isolated mitochondria of the same species the membrane role of phosphatidylcholine is replaced almost entirely by phosphatidylethanol-amine (Dawson, 1966).