The stability of proton T2 effects of oxygen‐17 water in experimental cerebral ischemia
- 1 November 1991
- journal article
- research article
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 22 (1) , 167-174
- https://doi.org/10.1002/mrm.1910220118
Abstract
The gerbil model of unilateral cerebral ischemia has been used to test the temporal and spatial stability of the MRI T2 effects of oxygen-17 water. Following unilateral carotid ligation, symptomatic animals were given a single large intraperitoneal injection of H2 17O and the distribution and stability of the brain T2 effects were followed with a spin-echo sequence. In contrast to the ischemic areas, the perfused tissue shows a marked and prolonged loss in intensity with little evidence of diffusion of the T2 effect of 17O into the ischemic tissue. © 1991 Academic Press, Inc.Keywords
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