Regulation of the Accumulation and Function of p53 by Phosphorylation of Two Residues within the Domain That Binds to Mdm2
Open Access
- 1 January 2002
- journal article
- Published by Elsevier
- Vol. 277 (3) , 1864-1871
- https://doi.org/10.1074/jbc.m108881200
Abstract
No abstract availableKeywords
This publication has 43 references indexed in Scilit:
- Regulation of p53 expression by the RAS-MAP kinase pathwayOncogene, 2001
- Phosphorylation of serines 15 and 37 is necessary for efficient accumulation of p53 following irradiation with UVOncogene, 2001
- Human p53 Is Phosphorylated on Serines 6 and 9 in Response to DNA Damage-inducing AgentsJournal of Biological Chemistry, 2000
- Damage-mediated Phosphorylation of Human p53 Threonine 18 through a Cascade Mediated by a Casein 1-like KinaseJournal of Biological Chemistry, 2000
- Mdm2 association with p53 targets its ubiquitinationOncogene, 1998
- DNA damage activates p53 through a phosphorylation–acetylation cascadeGenes & Development, 1998
- Mdm2 promotes the rapid degradation of p53Nature, 1997
- Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation DomainScience, 1996
- The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivationCell, 1992
- Extension of Multiple Range Tests to Group Means with Unequal Numbers of ReplicationsPublished by JSTOR ,1956