Glucose transport by short loops of Henle in the rat.

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Abstract
Short loops of Henle were artificially perfused with saline solutions containing 5 or 0 mM-glucose in the presence and absence of phlorizin. Net fluid reabsorption was greater when glucose, but no phlorizin, was present than in all other series. Glucose was reabsorbed from glucose-containing perfusate, and this was abolished by phlorizin. Secretion of glucose occurred into the perfusate which initially contained no glucose, and this secretion was enhanced by phlorizin. Na reabsorption was inhibited by phlorizin when glucose was present, but enhanced by phlorizin when glucose was absent. Apparently, there was secretion of some osmotically active solute in all series. Its secretion was enhanced by phlorizin in the absence of glucose.