Genetic effects of chlorinated anilines and azobenzenes onSalmonella typhimurium
- 1 January 1980
- journal article
- Published by Springer Nature in Archives of Environmental Contamination and Toxicology
- Vol. 9 (5) , 533-541
- https://doi.org/10.1007/bf01056933
Abstract
The mutagenicity of 19 herbicide-derived chlorinated azobenzenes and structurally related chlorinated anilines and nitrobenzenes was assayed towards several strains ofS. typhimurium, using the plate incorporation method and the fluctuation test, in the presence or in the absence of liver post-mitochondrial fractions, in aerobic and anaerobic conditions. Positive results were obtained with 4,4′-dichloroazobenzene, 4,4′-dichloroazoxybenzene, 3,4-dichloronitrobenzene and, to a much lesser extent, with 3,4,3′,4′-tetrachloroazobenzene. No mutagenic effect was observed with 2,3,7,8-tetrachlorodibenzo-p-dioxin in any condition.Keywords
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