Methods for Preparation of Suspensions of Buffy Coat-Poor Red Blood Cells for Transfusion: Including a Report of 50 Transfusions of Suspensions of Buffy Coat-Poor Red Blood Cells Prepared by a Dextran Sedimentation Method

Abstract
Several methods are described for preparing suspensions of buffy coat-poor red cells for transfusion to patients having recurrent febrile transfusion reactions caused by sensitivity to buffy coat. Clinical trials using a centrifugation method (6 transfusions) and a dextran sedimentation method (50 transfusions) are reported. The use of suspensions of buffy coat-poor red cells has proved to be of great value in the transfusion therapy of buffy coat-sensitive patients.

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