Pyrrolizidine alkaloid analogues. Synthesis of ten-membered macrocyclic diesters of (+)-retronecine
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 3,p. 611-613
- https://doi.org/10.1039/p19850000611
Abstract
The first synthesis of ten-membered macrocyclic pyrrolizidine diesters [(3)–(6)] has been achieved by treatment of (+)-retronecine (2) with succinic anhydride, (±)-trans-cyclohexane-1,2-dicarboxylic anhydride, and phthalic anhydride respectively, followed by lactonisation via the pyridine-2-thiol esters.This publication has 5 references indexed in Scilit:
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