Comparison of Normal Blood Picture of Young Adults from 18 Inbred Strains of Mice

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Abstract
Characteristic level of RBC number, hematocrit level, mean RBC vol., hemoglobin content, reticulo-cyte %, WBC number, and granulocyte % is given for 2-3 month virgin females and males of 18 inbred strains. Analysis of variance disclosed highly significant genetic differences in RBC number, hematocrit, and hemoglobin, closely inter-correlated so that only one strain differed significantly in mean cell vol.; significant strain difference in WBC number and granulocyte %, and significant sex difference in granulocyte % only. There was a correlation between strain means for total WBC number and % agranulocytes, indicating more extensive genetic variation in lymphocytes than in granulocytes. In this data, the observed strain differences do not appear to be related to differences in other known physiol. characteristics.
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