Interferon‐γ–Mediated Antiviral Immunity against Orthopoxvirus Infection Is Provided by γδ T Cells
Open Access
- 1 June 2006
- journal article
- Published by Oxford University Press (OUP) in The Journal of Infectious Diseases
- Vol. 193 (11) , 1606-1607
- https://doi.org/10.1086/503438
Abstract
To the Editor —Abate et al. [1] reported increases in the numbers of vaccinia virus (VV)–responding CD4+ and CD8+ T cells in recipients of smallpox vaccine, compared with those in nonvaccinated control subjects. The population of interferon (IFN)–γ–producing γδ T cells was also expanded in vaccinated persons, suggesting that, in addition to CD4+ and CD8+ αβ T cells, γδ T cells might be involved in orthopoxvirus-induced immune responsesKeywords
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