The Effect of Ellagic Acid on Coagulation in Vivo

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Abstract
Ellagic acid shortens the silicone and glass clotting times of the blood of dogs, cats, rabbits and rats. The silicone clotting time is reduced so as to make it almost equal to the normal glass clotting time for 5 to 30 minutes after the injection of the agent. There is occasional acceleration of thromboplastin generation in dogs. No other clotting factors were altered significantly in our experiments. There were no obvious toxic effects of ellagic acid, and it appears to decrease bleeding in normal animals.