Transferable Resistance to Cefotaxime in NosocomialKlebsiella pneumoniaeandEscherichia coliStrains Due to Their Production of Extended-Spectrum Beta-Lactamase in Slovakia
- 1 January 1995
- journal article
- research article
- Published by Taylor & Francis in Journal of Chemotherapy
- Vol. 7 (1) , 16-20
- https://doi.org/10.1179/joc.1995.7.1.16
Abstract
Transferable resistance to cefotaxime was demonstrated in 21 nosocomial strains of Klebsiella pneumoniae and Escherichia coli subsequently isolated from patients in two large University clinics. Using the double-disk diffusion test, we could detect, in each such strain, as well as in E. coli 3110 K-12 transconjugants after the transfer, the production of an Extended Spectrum Beta-Lactamase (ESBL). Ceftibuten was demonstrated to be effective against the majority of strains studied.Keywords
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