GLYCEMIC EFFECTS OF SOLANINE IN RATS
- 1 January 1967
- journal article
- research article
- Published by Elsevier in The Japanese Journal of Pharmacology
- Vol. 17 (4) , 652-658
- https://doi.org/10.1254/jjp.17.652
Abstract
The alkaloid, solanine, increased blood sugar level in intact rats. This hyperglycemia was prevented by pretreatment with either adrenergic blockers or reserplne, not with chlorpromazine. Inhibition of peripheral utilization of glucose was observed in glucose tolerance tests. Hypoglycemia was found in adrenalcctomized rats. There was considerable sex difference in solanine induced hyperglycemia. These phenomena were found only with intraperitoneal administration.This publication has 11 references indexed in Scilit:
- Effects of toxic chemicals on some adaptive liver enzymes, liver glycogen, and blood glucose in fasted ratsBiochemical Pharmacology, 1966
- LIVER NECROSIS FROM PARACETAMOLBritish Journal of Pharmacology and Chemotherapy, 1966
- Neurotropic drugs, electroshock, and carbohydrate metabolism in the ratBiochemical Pharmacology, 1966
- Effects of d-amphetamine on blood glucose and tissue glycogen levels of isolated and aggregated miceBiochemical Pharmacology, 1965
- Chlorpromazine and glucose metabolismInternational Journal of Neuropharmacology, 1964
- STUDIES ON THE HYPERGLYCAEMIA INDUCED BY CHLORPROMAZINE IN RATSBritish Journal of Pharmacology and Chemotherapy, 1964
- Toxic Effects of Potato Sprouts and of Solanine Fed to Pregnant RatsExperimental Biology and Medicine, 1961
- Effect of Adrenergic Blocking Agents on Fatty Acid Mobilization during Fasting.Experimental Biology and Medicine, 1959
- SOME ACTIONS OF CHLORPROMAZINEBritish Journal of Pharmacology and Chemotherapy, 1956
- Glycemic Effects of Chlorpromazine in the Mouse, Hamsterand RatExperimental Biology and Medicine, 1955