Detection of Astrovirus in Premature Infants With Necrotizing Enterocolitis

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Abstract
Background: Necrotizing enterocolitis (NEC) is a major cause of mortality and morbidity in very low birth weight infants (P < 0.001) but not for severity of illness, need for surgical intervention, or mortality. Conclusions: This study demonstrates that HAstV may be associated with the development of NEC in a subgroup of patients and provides further evidence for the important role of gastrointestinal viral infections in this most common gastrointestinal emergency in premature infants. HAstV should be included in microbiological examination of stool specimens in patients with NEC.

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