CHARACTERIZATION OF A FACTOR FORMED IN THE COURSE OF ADENOVIRUS INFECTION OF TISSUE CULTURES CAUSING DETACHMENT OF CELLS FROM GLASS

Abstract
Most adenoviruses produce in tissue culture a factor which in low dilutions detaches HeLa or KB cells from glass surfaces within 1/2 to 4 hours after inoculation. The active material is non-dialyzable, trypsin sensitive, relatively resistant to heat and UV light, and smaller than the infectious virus particle. The cell-detaching factor contains adenovirus antigens, but is not serologically identical with the infectious virus or the soluble complement fixing antigen.
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