Production, properties, and thrombin inhibitory mechanism of hirudin amino-terminal core fragments.
Open Access
- 1 December 1990
- journal article
- abstracts
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 265 (36) , 22159-22166
- https://doi.org/10.1016/s0021-9258(18)45684-0
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- The complete amino acid sequence of hirudin, a thrombin specific inhibitorPublished by Wiley ,2001
- Affinity labeling of lysine-149 in the anion-binding exosite of human .alpha.-thrombin with an N.alpha.-(dinitrofluorobenzyl)hirudin C-terminal peptideBiochemistry, 1990
- Preparation of monoclonal antibodies to hirudin and hirudin peptidesEuropean Journal of Biochemistry, 1990
- The structural elements of hirudin which bind to the fibrinogen recognition site of thrombin are exclusively located within its acidic C‐terminal tailFEBS Letters, 1990
- Antithrombin activity of the hirudin N‐terminal core domain residues 1–43FEBS Letters, 1990
- Solution structure of recombinant hirudin and the Lys-47 .fwdarw. Glu mutants: a nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing studyBiochemistry, 1989
- Use of site-directed mutagenesis to investigate the basis for the specificity of hirudinBiochemistry, 1988
- Interaction of site specific hirudin variants with α‐thrombinFEBS Letters, 1988
- Antithrombin properties of C‐terminus of hirudin using synthetic unsulfated Nα‐acetyl‐hirudin45–65FEBS Letters, 1987
- The functional domain of hirudin, a thrombin‐specific inhibitorFEBS Letters, 1983