Serum Esterolytic Activity in a Wide Variety of Diseases

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Abstract
THERE have been several recent reports suggesting the diagnostic value of measuring the hydrolysis of two arginine substrates, benzoyl-L-arginine ethyl ester (BAEE)1 and benzoyl arginine amide (BAA)2 , 3 by serum of patients with acute pancreatitis and carcinoma of the pancreas. Although more than one component of serum has been shown to be capable of hydrolyzing these substrates, it has been suggested that trypsin may be elevated in pancreatic disease and could conceivably account for the enhanced hydrolysis of the arginine substrates. In any event, if significant hydrolysis could be established in one or both of these diseases, an appreciable diagnostic advance . . .

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