Immunogenetic Factors in Skin Cancer
- 19 September 1991
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 325 (12) , 884-887
- https://doi.org/10.1056/nejm199109193251210
Abstract
The malignant degeneration of normal tissues is a multifactorial process in which elements in the host and the environment conspire to produce clinical cancer. Except under rather rare circumstances, no element alone is sufficient. It is generally believed that the relative contributions of host and environment vary considerably both among tumor types and among individual patients. In the case of skin cancer, there is information implicating both host and environmental factors, although that information is still incomplete. From the environmental standpoint, ultraviolet B (UVB) radiation in sunlight is known to make an essential and critical contribution to the development of . . .Keywords
This publication has 6 references indexed in Scilit:
- Relation between Skin Cancer and HLA Antigens in Renal-Transplant RecipientsNew England Journal of Medicine, 1991
- Genetic basis of the effects of ultraviolet light B on cutaneous immunity. Evidence that polymorphism at the Tnfa and Lps loci governs susceptibilityImmunogenetics, 1990
- Susceptibility to Effects of UVB Radiation on Induction of Contact Hypersensitivity as a Risk Factor for Skin Cancer in HumansJournal of Investigative Dermatology, 1990
- The relative importance of risk factors in nonmelanoma carcinomaArchives of Dermatology, 1980
- Collaborative United Kingdom-Australasian study of cancer in patients treated with immunosuppressive drugs.BMJ, 1979
- Non-melanoma skin cancer among caucasians in four areas of the United StatesCancer, 1974