Immunogenetic Factors in Skin Cancer

Abstract
The malignant degeneration of normal tissues is a multifactorial process in which elements in the host and the environment conspire to produce clinical cancer. Except under rather rare circumstances, no element alone is sufficient. It is generally believed that the relative contributions of host and environment vary considerably both among tumor types and among individual patients. In the case of skin cancer, there is information implicating both host and environmental factors, although that information is still incomplete. From the environmental standpoint, ultraviolet B (UVB) radiation in sunlight is known to make an essential and critical contribution to the development of . . .