Effects of Raloxifene on Serum Lipids and Coagulation Factors in Healthy Postmenopausal Women

Abstract
MILLIONS OF postmenopausal women currently face a difficult dilemma: whether they should or should not take estrogen replacement. Estrogen use may protect against osteoporosis and heart disease, but may increase the risks of breast and endometrial cancers.1 Thus, there could be serious consequences in choosing to take estrogen, or in choosing not to take estrogen. Nearly half of postmenopausal women who begin hormone treatment discontinue use within 1 year.2 This is believed to be because of lingering concerns they may have about the long-term hazards of this treatment or unacceptable adverse effects such as vaginal bleeding and breast tenderness.