New Antihepatotoxic Naphtho-pyrone Glycosides from the Seeds ofCassia tora1
- 1 June 1989
- journal article
- research article
- Published by Georg Thieme Verlag KG in Planta Medica
- Vol. 55 (03) , 276-280
- https://doi.org/10.1055/s-2006-962003
Abstract
Two new naphtho-pyrone glycosides, 9-[(β-D-glucopyranosyl-(1→6)-O-β-D-glucopyranosyl)oxy]-10-hydroxy-7-methoxy-3-methyl-1H-naphtho[2,3-c]pyran-1 -one (5) and 6-[(α-apiofuranosyl-(1→6)-O-β-D-glucopyrano-syl)oxy]-rubrofusarin (6), together with cassiaside (3) and rubrofusarin-6-β-gentiobioside (4) were isolated from the seeds of Cassia tora L. Their structures were elucidated on the basis of chemical and spectral data. The naphtho-γ-pyrone glycosides (3, 4, and 6) were found to have significant hepato-protective effects against galactosamine damage, which were higher than that of silybin from Silybum marianum.This publication has 3 references indexed in Scilit:
- Anthraquinone glycosides from the seeds of Cassia tora☆Phytochemistry, 1989
- WEDELOLACTONE AND COUMESTAN DERIVATIVES AS NEW ANTIHEPATOTOXIC AND ANTIPHLOGISTIC PRINCIPLES1988
- Inhibitors of adenosine 3',5'-cyclic monophosphate phosphodiesterase in cassia seed.CHEMICAL & PHARMACEUTICAL BULLETIN, 1984