Inhibitors of adenosine 3',5'-cyclic monophosphate phosphodiesterase in cassia seed.
- 1 January 1984
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 32 (8) , 3075-3078
- https://doi.org/10.1248/cpb.32.3075
Abstract
Aurantio-obtusin and obtusin were identified as inhibitors of cAMP phosphodiesterase in seeds of Cassia obtusifolia and Cassia tora. The structure-activity relationships of 22 anthraquinones and 17 analogous compounds were studied. Anthraquinones of the emodin and obtusin types were generally more inhibitory towards cAMP phosphodiesterase than other types of anthraquinones, anthrones and lactones.This publication has 5 references indexed in Scilit:
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