Molecular mechanics and dynamics studies on two structurally related amide-modified DNA backbones for antisense technology
- 31 March 1995
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 3 (3) , 321-335
- https://doi.org/10.1016/0968-0896(95)00029-g
Abstract
No abstract availableKeywords
This publication has 33 references indexed in Scilit:
- Amides as a New Type of Backbone Modification in OligonucleotidesAngewandte Chemie International Edition in English, 1994
- Antisense Oligonucleotides with Alternating Phosphodiester-"Amide-3" LinkagesSynlett, 1994
- Synthesis of thymidine dimer derivatives containing an amide linkage and their incorporation into oligodeoxyribonucleotidesTetrahedron Letters, 1993
- Current concepts in antisense drug designJournal of Medicinal Chemistry, 1993
- Synthesis and binding properties of pyrimidine oligodeoxynucleoside analogs containing neutral phosphodiester replacements: the formacetal and 3'-thioformacetal internucleoside linkagesThe Journal of Organic Chemistry, 1993
- Amides as Substitute for the Phosphodiester Linkage in Antisense OligonucleotidesSynlett, 1993
- Synthesis of Oligonucleotide Analogues with Modified BackbonesSynlett, 1993
- Oligonucleosides: synthesis of a novel methylhydroxylamine-linked nucleoside dimer and its incorporation into antisense sequencesJournal of the American Chemical Society, 1992
- Therapeutic Applications of OligonucleotidesAnnual Review of Pharmacology and Toxicology, 1992
- Antisense oligonucleotides: a new therapeutic principleChemical Reviews, 1990