Biologically active conformation of tuftsin
- 1 March 1984
- journal article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 23 (3) , 271-275
- https://doi.org/10.1111/j.1399-3011.1984.tb02719.x
Abstract
The main features of the assumed biologically active conformation of the tuftsin molecule have been described using the energy calculations as well as the n.m.r. and CD‐spectroscopy measurements performed for the conformationally rigid active cycloanalogue, Thr‐L‐ys‐Pro‐Arg. The biologically active conformation has been shown to be of BBRB or BLRB backbone type with the trans‐conformation of proline residue.Keywords
This publication has 11 references indexed in Scilit:
- 13C Nuclear Magnetic Resonance and Circular Dichroism Studies of the Tuftsin Conformation in WaterEuropean Journal of Biochemistry, 1980
- TUFTSIN ANALOGS WITH D‐AMINO ACID RESIDUES*International Journal of Peptide and Protein Research, 1980
- Nuclear magnetic resonance studies on the structure of the tetrapeptide tuftsin L-threonyl-L-lysyl-L-prolyl-L-arginine, and its pentapeptide analog L-threonyl-L-lysyl-L-prolyl-L-prolyl-L-arginineBiochemistry, 1979
- Infrared Spectroscopic Investigations of Tuftsin and Its AnalogsEuropean Journal of Biochemistry, 1979
- THEORETICAL CONFORMATIONAL ANALYSIS OF OXYTOCIN MOLECULEInternational Journal of Peptide and Protein Research, 1979
- Conformational Energy Study of TuftsinMacromolecules, 1978
- Synthesis and properties of tuftsin, L-threonyl-L-lysil-L-prolyl-L-arginineCollection of Czechoslovak Chemical Communications, 1976
- Energy parameters in polypeptides. VII. Geometric parameters, partial atomic charges, nonbonded interactions, hydrogen bond interactions, and intrinsic torsional potentials for the naturally occurring amino acidsThe Journal of Physical Chemistry, 1975
- Refinement of the angular dependence of the peptide vicinal NHCαH coupling constantTetrahedron, 1973
- The characteristics, isolation and synthesis of the phagocytosis stimulating peptide tuftsinBiochemical and Biophysical Research Communications, 1972