Monoclonal Anti‐A from a Hybrid‐Myeloma: Evaluation as a Blood Grouping Reagent
- 1 September 1980
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 39 (3) , 134-140
- https://doi.org/10.1111/j.1423-0410.1980.tb01848.x
Abstract
A monoclonal anti‐A antibody has been evaluated and found suitable for use as a potent routine ABO grouping reagent, without the use of additives. The IgM anti‐A (MH2/6D4) is secreted into the tissue culture supernatant by a permanent line of cloned cells derived by fusion of anti‐A producing spleen cells and a mouse myeloma cell line. This is a costeffective reagent which should reduce production costs by over 50%. This reagent has the advantages inherent in monoclonal antibodies among them the availability of unlimited quantities of unvarying antibody of known properties.This publication has 9 references indexed in Scilit:
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