Biophysical mechanisms of damage by fast ions to mammalian cells in vitro
- 1 March 1985
- journal article
- research article
- Published by IOP Publishing in Physics in Medicine & Biology
- Vol. 30 (3) , 255-258
- https://doi.org/10.1088/0031-9155/30/3/006
Abstract
As part of an investigation into better methods for specifying radiation quality for application to damage modelling the authors have surveyed published data for fast ion irradiation of mammalian cells in vitro. On the basis of the damage mechanism described here, optimum damage should be caused by accelerated ions having mean free paths for ionisation of 2 nm regardless of ion type with obvious implications for radiotherapy.Keywords
This publication has 5 references indexed in Scilit:
- Mutation and Inactivation of Cultured Mammalian Cells Exposed to Beams of Accelerated Heavy IonsInternational Journal of Radiation Biology, 1979
- The Effect of Oxygen on Impairment of the Proliferative Capacity of Human Cells in Culture by Ionizing Radiations of Different LETInternational Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1966
- The Action of Fast Heavy Ions on Biological Material: II. Effects on T1 and φX-174 Bacteriophage and Double-Strand and Single-Strand DNARadiation Research, 1964
- Penetration of Protons, Alpha Particles, and MesonsAnnual Review of Nuclear Science, 1963
- Study of the Radiosensitivity of Dry Preparations of Lysozyme, Trypsin, and Deoxyribonuclease, Exposed to Accelerated Nuclei of Hydrogen, Helium, Carbon, Oxygen and NeonRadiation Research Supplement, 1960