EVIDENCE FOR HETEROSIS IN THE HLA SYSTEM

  • 1 January 1981
    • journal article
    • research article
    • Vol. 33  (6) , 894-899
Abstract
The number of persons with homozygous HLA haplotypes in several groups of South American Indians was 39% less than that expected assuming unmodified equlibrium. In a subpopulation of 122 persons whose parents'' HLA constitutions were known, there were 56% fewer homozygous persons than expected. This deficit was widely distributed in different haplotypes and different tribal groups.