Stimulation of leucomycin production by magnesium phosphate and its relevance to nitrogen catabolite regulation
- 1 November 1980
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 18 (5) , 691-695
- https://doi.org/10.1128/aac.18.5.691
Abstract
Addition of magnesium phosphate [Mg3(PO4)2 x 8H2O] to a complex medium or to an ammonium ion-containing, chemically defined medium stimulated leucomycin production by Streptomyces kitasatoensis. Ammonium ions in high concentrations inhibited leucomycin production, but their limitation by magnesium phosphate led to the high production of the antibiotic.This publication has 9 references indexed in Scilit:
- Nitrogen nutrition and regulation of cephalosporin production in Streptomyces clavuligerusCanadian Journal of Microbiology, 1979
- EFFECT OF PRIMARY METABOLITES ON SECONDARY METABOLISMAnnual Review of Microbiology, 1977
- STUDY OF PECULIAR PROPERTIES OF FUSIDIN BIOSYNTHESIS BY FUSIDIUM-COCCINEUM, STRAIN-257A1977
- STUDY ON REGULARITIES OF ACT ANTIBIOTICUS GROWTH AND OLEANDOMYCIN BIOSYNTHESIS1976
- Biosynthetic studies using carbon-13 enriched precursors on the 16-membered macrolide antibiotic leucomycin A3Journal of the American Chemical Society, 1975
- Chemical and biological studies on 16-membered macrolide antibiotics.The Journal of Antibiotics, 1975
- Relationship between Fatty‐Acid and Phenol Synthesis in Aspergillus fumigatusEuropean Journal of Biochemistry, 1974
- Observations on Streptomyces griseus: II. Nitrogen Sources for Growth and Streptomycin Production.1948
- Observations on Streptomyces griseusJournal of Bacteriology, 1948