Time-gated biological imaging by use of colloidal quantum dots
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- 1 June 2001
- journal article
- Published by Optica Publishing Group in Optics Letters
- Vol. 26 (11) , 825-827
- https://doi.org/10.1364/ol.26.000825
Abstract
The long (but not too long) fluorescence lifetime of CdSe semiconductor quantum dots was exploited to enhance fluorescence biological imaging contrast and sensitivity by time-gated detection. Significant and selective reduction of the autofluorescence contribution to the overall image was achieved, and enhancement of the signal-to-background ratio by more than an order of magnitude was demonstrated.Keywords
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