Cytogeneticity of Quinalphos and Methyl Parathion in Human Peripheral Lymphocytes

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Abstract
1 Four different concentrations of quinalphos and methyl parathion were tested on human peripheral lymphocytes over different time periods, for the analysis of chromosomal aberrations and sister chromatid exchanges (SCEs). 2 A significant increase in chromosomal aberrations was observed when cells were treated with quinalphos for 48 and 72 h and a significant increase in SCEs was observed at all the concentrations and over all the time periods. 3 Methyl-parathion did not induce chromosomal aberrations but it did induce SCEs significantly over all time periods.