Effect of Chemical Agents on Skeletal Content and Excretion of Injected Strontium89.
- 1 July 1953
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 83 (3) , 550-554
- https://doi.org/10.3181/00379727-83-20414
Abstract
The admn. of the salts of ethylene diamine tetra-acetic acid (EDTA) under the most favorable conditions for its action had no effect on the skeletal distr. of injected carrier-free Sr89. Zr citrate administered prior to the injn. of Sr89 resulted in a level of Sr89 in the skeleton at 5 days, 40% lower than that found in the controls. A corresponding increase in Sr89 excretion was also noted. Combined admn. of EDTA with Zr citrate and with BAL were without effect on the skeletal distr. of injected Sr89. Possible explanations for the effect of the various chemical agents employed are discussed.Keywords
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